4q25 Atrial Fibrillation Risk Genotype Test

(Prevalence: 20-30%)

This test identifies individuals with an increased genetic risk of developing atrial fibrillation (Afib). Atrial fibrillation is a potential dangerous arrhythmia of the heart that can increase a patient’s risk of forming blood clots that can cause a stroke.

Two 4q25 variants, rs2200733 and rs10033464, have been associated with a 1.4-1.5 fold increased risk of developing atrial fibrillation. This association has been observed in multiple studies, and is especially seen in subjects over 60 years old. 1

4q25 Test

Patients who are positive for 4q25, but who already have Afib, may not respond well to ablation therapy . . . so this test helps differentiate who might be a better candidate for management with medication. 

Who should consider getting the 4q25 test?

Individuals with a family history of atrial fibrillation

People who have had cryptogenic stroke (stroke without an identifiable cause)

Those who already have Afib and are considering ablation therapy to treat it

Patients who have unexplained elevations of NT pro-BNP (a blood biomarker that can indicate stress on the heart)

Do something today for a better tomorrow! 

Make an appointment now for advanced testing. We are here to help.

Advanced Genetic Tests

Click Below to Learn More

APO E
A gene that affects the way our body processes fat and alcohol, sometimes referred to as the "Alzheimer’s gene."

APO E

MTHFR
A gene that affect the body’s ability to detoxify and utilize certain B vitamins (which affect brain, heart, and infant health).

MTHFR

SLOCO1B1
A gene that can identify who is at increased risk of having side effects from statin cholesterol drugs.

SLOCO1B1

KIF 6
A gene that increases the risk of heart disease, but can determine who would particularly benefit from statin cholesterol medications

KIF 6

9P21
A gene that can identify individuals who may be at an increased risk of premature heart disease.

9P21

4Q25
A gene that can identify who is at increased risk of developing atrial fibrillation (a potentially dangerous arrhythmia of the heart).

4Q25

Prothrombin Mutation
A gene that increases the risk of developing blood clots

Prothrombin Mutation

Factor V Leiden
A gene that increases the risk of developing blood clots

Factor V Leiden

CYP2C19
A gene that determines if the blood thinner Plavix is metabolized normally, or whether this medication could lead to increased clotting or bleeding.

CYP2C19

Advanced Genetic Tests

Click Below to Learn More

APO E
A gene that affects the way our body processes fat and alcohol, sometimes referred to as the "Alzheimer’s gene."

APO E

MTHFR
A gene that affect the body’s ability to detoxify and utilize certain B vitamins (which affect brain, heart, and infant health).

MTHFR

SLOCO1B1
A gene that can identify who is at increased risk of having side effects from statin cholesterol drugs.

SLOCO1B1

KIF 6
A gene that increases the risk of heart disease, but can determine who would particularly benefit from statin cholesterol medications

KIF 6

9P21
A gene that can identify individuals who may be at an increased risk of premature heart disease.

9P21

4Q25
A gene that can identify who is at increased risk of developing atrial fibrillation (a potentially dangerous arrhythmia of the heart).

4Q25

Prothrombin Mutation
A gene that increases the risk of developing blood clots

Prothrombin Mutation

Factor V Leiden
A gene that increases the risk of developing blood clots

Factor V Leiden

CYP2C19
A gene that determines if the blood thinner Plavix is metabolized normally, or whether this medication could lead to increased clotting or bleeding.

CYP2C19